Vitamin K2

 

Vitamin K2 is considered by the modern science as one of the most important ingredients on the list of nutrients for cardiovascular diseases prevention. Vitamin K2 used in Arginext is a fermentation extract of natural vitamin K2 manufactured using bascillus subtilis natto (MenaQ7® )

It is noteworthy that vitamin K naturally comes in two forms: K1 (phylloquinone) and K2 (menaquinone or MK). However, only vitamin K2 had an effect on coronary calcification, but K1 did not.There is a synthetic (man made) form – Vitamin K3 (menadione), widely used in animal husbandry, which interferes with the function of glutathione, one of the body’s natural antioxidants, resulting in oxidative damage to cell membranes.


Why is Vitamin K2 Beneficial for Your Heart?

A study, published in medical journal on Atherosclerosis, found that high dietary intake of vitamin K2 can reduce coronary calcification (hardening of the arteries) that further lowers your risk of heart disease. Another research (Rotterdam Study) also demonstrated the beneficial effect of vitamin K2 on increasing lifespan. It showed that, if people had consumed 45 mcg of K2 daily, they tended to live seven years longer than those who were getting 12 mcg per day. At the same time, as one of leading researchers in the field of vitamin K – Dr. Cees Vermeer notes, deficiency in vitamin K in people as common as deficiency in vitamin D.

The presence of atherosclerotic plaques in arterial walls is one of the common conditions associated with cardiovascular diseases. Plaque rupture can cause blood clot formation (thrombogenesis) that appears to be the usual cause of a myocardial infarction (heart attack) or stroke. Vitamin K2 activates a protein hormone called osteocalcin, which binds calcium into your bone with help of vitamin D that prevent calcium from depositing into your arteries. In other words, without vitamin K2, the calcium might build up in your coronary arteries rather than in your bones. Vitamin K-dependent proteins – matrix Gla protein (MGP) and Gla-rich protein (GRP) – are secreted by various cell types, such as vascular smooth muscle cells (VSMCs) in arterial vessel walls. These proteins are also important for the prevention of calcification of soft tissues, including cartilage, vasculature, skin, and trabecular meshwork cells in the eye.

Vitamin K and vitamin D work together to increase MGP in the body, which congregates around the elastic fibers of your tunica media (arterial lining), guarding them against calcium crystal formation. Since nearly 100 percent of people do not get adequate amounts of vitamin K2 from their diet, Professor Cees Vermeer notes that “non-supplemented healthy adults are insufficient in vitamin K to a level that 30 percent of their MGP is synthesized in an inactive form. So, protection against cardiovascular calcification is only 70 percent in the young, healthy population, and this figure decreases at increasing age.”

As it was also demonstrated by recent studies linking calcium supplements to heart attacks, if you take calcium and vitamin D but are deficient in vitamin K2, you could be worse off than if you were not taking those supplements at all.

How Much Vitamin K2 Is Need?

The exact dosing of daily intake was not officially determined. Although allergic reaction is possible, there is no known toxicity associated with high doses (dietary or supplemental) of ether the phylloquinone (vitamin K1) or menaquinone (vitamin K2). Acorrding to Dr. Vermeer, the daily dose should be up to 185 mcg daily for adults. Taking one scoop of Arginext daily will provide you with all the K2 you need (180 micrograms). 

In Arginext we use only the trusted source for natural vitamin K2  ( MenaQ7) – a fermentation extract manufactured from  bascillus subtilis natto. The traditional Japanese dish Natto is rich in natural menaquinone-7 (Mk-7), and is the most bioavailable and bioactive form of supplemental vitamin K2 in the market. 

Additionally you will get 1000 IU of Vitamin D3 and other vital nutrients (including Magnesium, L-arginine and a number of viatmins) which will provide you with an inexpensive, but effective and tasty daily protection against development of cardiovascular diseases.

Other Reasons to Take Vitamin K2 Daily

Vitamin K is an extremely important vitamin to have in your diet; it may very well be the next vitamin D in terms of the numerous health benefits it may provide.

Improve Bone Density

Vitamin K serves as the biological “glue” that helps plug the calcium into your bone matrix therefore is one of the most important nutritional interventions for improving bone density.Studies have shown a daily intake vitamin K can be as effective as osteoporosis drugs, but with no side effects.

Stave off Varicose Veins

Inadequate levels of vitamin K may reduce the activity of the matrix GLA protein (MGP), which in turn has been identified as a key player in the development of varicosis, or varicose veins.

Lower Your Risk of Diabetes

According to the latest research from University Medical Center Utrecht in the Netherlands, people with the highest intakes of vitamin K from their diet had a 20 percent lower risk of diabetes compared with those with the lowest intakes. Later studies have also shown vitamin K can reduce the progression of insulin resistance.

Fight Cancer

Vitamin K has been found beneficial in the fight against non-Hodgkin lymphoma, liver, colon, stomach, prostate, nasopharynx, and oral cancers, and some studies have even suggested vitamin K may be used therapeutically in the treatment of patients with lung cancer, liver cancer, and leukemia.